Effects of seeding adipose-derived stem cells on electrospun nanocomposite used as chest wall graft in a murine model. Issue 10 (October 2017)

• Record Type: Journal Article
• Authors: Buschmann, Johanna; Balli, Eleni; Hess, Samuel C.; Stark, Wendelin J.; Cinelli, Paolo; Märsmann, Sonja; Welti, Manfred; Weder, Walter; Jungraithmayr, Wolfgang
• Is Part Of: Injury. Volume 48:Issue 10(2017)
• Page Start: 2080
• Page End: 2088
• Publication Date: 2017-10
• Subjects: Wounds and injuries -- Surgery -- Periodicals; Accidents -- Periodicals; Wounds and Injuries -- surgery -- Periodicals; Lésions et blessures -- Chirurgie -- Périodiques; Electronic journals; Electronic journals; 617.1
• DOI: 10.1016/j.injury.2017.08.004
• Languages: English
• ISSNs: 0020-1383

Abstract

Abstract: Objectives: Malignant neoplasms infiltrating the chest wall often requires resection of the thoracic wall. To replace the defect, Gore-Tex ® is usually employed as the gold standard material, however, Gore-Tex ® is inert and not degradable. Novel materials are nowadays available which allow a full bio-integration due to their non-toxic degradability. Additionally, stem cell seeding has the capacity to reduce inflammatory response towards such grafts, thus integrating it better into the host organism.