A bloodstream infection by Ruminococcus gnavus in a patient with a gall bladder perforation. (October 2017)

• Record Type: Journal Article
• Authors: Kim, Young Jin; Kang, Hee Yoon; Han, Yujin; Lee, Mi Suk; Lee, Hee Joo
• Is Part Of: Anaerobe. Volume 47(2017)
• Page Start: 129
• Page End: 131
• Publication Date: 2017-10
• Subjects: R. gnavus -- Bacteremia -- Gram stain -- MALDI-TOF MS; Anaerobic infections -- Periodicals; Anaerobic bacteria -- Periodicals; Bacterial diseases -- Periodicals; Computer network resources; Anaerobic protozoa -- Periodicals; 579.3
• DOI: 10.1016/j.anaerobe.2017.05.007
• Languages: English
• ISSNs: 1075-9964

Abstract

Abstract: Ruminococcus gnavus is frequently found among human gut microbiome. However, human bloodstream infections by R. gnavus have been reported only three times. Clinical details were lacking for one case; the other two cases with concurrent bacteremia in patients with diverticulitis. We report a case of R. gnavus bloodstream infection in a patient with a gall bladder perforation suggesting its association with damage to the gastrointestinal tract. R. gnavus was misidentified using biochemical test but 16S rRNA sequencing and Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry were useful for correct identification. With the advancement of identification method in clinical laboratory, more frequent identification of R. gnavus from clinical specimens is expected. Highlights: We report a bacteremia caused by Ruminococcus gnavus in a patient with a gall bladder perforation. This bacteria is human gut flora and could be misidentified by conventional biochemical methods. R. gnavus was identified correctly through 16S rRNA sequencing and MALDI-TOF MS. More clinical isolates are expected to be found owing to development of identification methods.