Atypical presentation of calvarial metastasis of renal cell carcinoma in an adolescent: A rare case diagnosed on fine needle aspiration cytology with literature review. Issue 5 (21st January 2015)

• Record Type: Journal Article
• Authors: Gaur, Kavita; Mandal, Shramana; Gondal, Ranjana; Singh, Daljit
• Is Part Of: Diagnostic cytopathology. Volume 43:Issue 5(2015:May)
• Page Start: 412
• Page End: 415
• Publication Date: 2015-01-21
• Subjects: adolescent -- calvarium -- metastasis -- renal cell carcinoma; Cytodiagnosis -- Periodicals; Pathology, Cellular -- Periodicals; Cytology -- Periodicals; 616.07582
• DOI: 10.1002/dc.23245
• Languages: English
• ISSNs: 8755-1039

Abstract

Abstract : Renal cell carcinoma (RCC) is a complex and challenging neoplasm both in terms of treatment as well as diagnosis. Its unpredictable biological behavior and many deceptive appearances can sometimes bewilder the pathologist. We hereby report a rare case of a 17 year old girl presenting with an occipital swelling and importantly no prior documents at the time of aspiration. Fine needle aspiration cytology showed features of metastatic carcinoma with the following possibilities; metastatic RCC, melanoma, and hepatocellular carcinoma. Further detailed history of the patient and investigations were advised. Intraoperative squash smears also showed similar features. Histopathology of the lesion showed features of metastatic RCC. This case highlights the fact that a skull lesion in rare cases may be the presenting sign of an underlying malignancy. In the absence of key documents, providing the correct diagnosis may become very challenging and cytomorphology alone can be extremely helpful. Diagn. Cytopathol. 2015;43:412–415. © 2015 Wiley Periodicals, Inc.