Impact of single anaerobic exercise on delayed activation of endothelial xanthine oxidase in men and women. (2nd November 2017)

• Record Type: Journal Article
• Authors: Wiecek, Magdalena; Maciejczyk, Marcin; Szymura, Jadwiga; Kantorowicz, Malgorzata; Szygula, Zbigniew
• Is Part Of: Redox report. Volume 22:Number 6(2017)
• Page Start: 367
• Page End: 376
• Publication Date: 2017-11-02
• Subjects: Xanthine oxidase -- oxidative stress -- anaerobic exercise -- sex differences -- muscle injuries; Free radicals (Chemistry) -- Pathophysiology -- Periodicals; Oxidation, Physiological -- Periodicals; 541.224
• DOI: 10.1080/13510002.2016.1238991
• Languages: English
• ISSNs: 1351-0002

Abstract

ABSTRACT: Objectives: The aim of the study was to evaluate the activity of xanthine oxidase (XO) in the blood of men and women during the first hour following a single anaerobic exercise (AN-EX), and after 24 hours of recovery, and to determine whether the changes in XO activity in the blood after AN-EX are dependent on anaerobic performance. Methods: Ten men and ten women performed a single AN-EX. Blood was collected before and five times after completion of the AN-EX. The activity of XO was determined. Results: In both groups, a significant ( P < 0.05) increase in blood XO activity was found only 24 hours after the AN-EX. The increased activity of XO in men was significantly lower than in women ( P < 0.05). Negative correlations were found between the increase in XO activity in the blood plasma 24 hours after the AN-EX and anaerobic power, the total work performed during the AN-EX and the power decrease. Discussion: In the first hour after the single AN-EX, XO activity in the blood of women and men did not change, but after 24 hours of recovery, it was significantly higher compared to baseline levels in both sexes. Single AN-EX causes a smaller increase in XO activity in people with higher anaerobic performance.