A fluorescence-enhanced probe for rapid detection of formaldehyde and its application for cell imaging. Issue 37 (12th September 2017)

• Record Type: Journal Article
• Authors: Wu, Feng; Zhang, Yue; Huang, Lei; Xu, Dan; Wang, Hongying
• Is Part Of: Analytical methods. Volume 9:Issue 37(2017)
• Page Start: 5472
• Page End: 5477
• Publication Date: 2017-09-12
• Subjects: Chemistry, Analytic -- Periodicals; Analytical biochemistry -- Periodicals; Chemical laboratories -- Standards -- Periodicals; 543.1905
• DOI: 10.1039/c7ay01786c
• Languages: English
• ISSNs: 1759-9660

Abstract

Abstract : An anthracene carboxyimide-based fluorescent probe was developed for rapid detection of formaldehyde in living cells with high sensitivity and selectivity. Abstract : A simple anthracene carboxyimide-based fluorescent probe has been readily developed for the detection of toxic formaldehyde (FA). The probe displays a remarkable fluorescence turn-on response towards FA based on the aldimine condensation reaction, which was confirmed by the HR-MS spectrum. The probe can quantitatively determine the level of FA with high selectivity and fast response (within 3 min). Furthermore, cell staining experiments indicate that the probe was cell membrane permeable and could be used for imaging FA in living cells with good performance. Therefore, this probe has promising applications for the detection of FA in living cells.