Facile Synthesis of In‐Chain, Multicomponent, Functionalized Polymers via Living Anionic Copolymerization through the Ugi Four‐Component Reaction (Ugi‐4CR). Issue 18 (31st July 2017)

• Record Type: Journal Article
• Authors: Shen, Heyu; Ma, Hongwei; Liu, Pibo; Huang, Wei; Han, Li; Li, Chao; Li, Yang
• Other Names: Wong Wai‐Yeung guestEditor.; Tang Ben Zhong guestEditor.
• Is Part Of: Macromolecular rapid communications. Volume 38:Issue 18(2017)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2017-07-31
• Subjects: living anionic polymerization -- multicomponent functionalization -- postpolymerization modification -- Ugi‐4CR; Macromolecules -- Periodicals; Polymers -- Periodicals; Chemistry -- Periodicals; 547.705
• DOI: 10.1002/marc.201700353
• Languages: English
• ISSNs: 1022-1336

Abstract

Abstract : The Ugi four‐component reaction (Ugi‐4CR) is a type of multicomponent reaction with attractive characteristics such as modularity, efficient conversation, being catalyst‐free, having mild conditions, and multifunctionality at one location. Via a modified strategy of Ugi‐4CR, a variety of functional groups are efficiently clicked on the well‐defined polymers synthesized by the copolymerization of styrene with Ugi‐1, 1‐diphenylethylene via living anionic polymerization. Abstract : By combining living anionic polymerization and the highly efficient Ugi four‐component reaction (Ugi‐4CR), in‐chain, multicomponent, functionalized polymers are facilely synthesized with efficient conversation and abundant functionality. l‐[4‐[ N, N ‐Bis(trimethylsilyl)‐amino]phenyl]‐l‐phenylethylene, which is redefined as Ugi‐DPE, is anionically copolymerized to synthesize the well‐defined in‐chain, multi‐amino functionalized polystyrene (P(St/DPE‐NH2 )), the backbone for the Ugi‐4CR, via hydrolysis of the copolymerization (P(St/Ugi‐DPE)). Subsequently, several functionalized components are facilely clicked onto P(St/DPE‐NH2 ) to investigate the model reactions of the in‐chain, multicomponent functionalization via the Ugi‐4CR. In contrast to conventional postpolymerization modifications, this approach proceeds under mild reaction conditions without the use of a catalyst and meanwhile an efficient conversation is obtained. Finally, the modified experimental results investigated in this research show the promising potential of the combination of well‐defined amino functionalized polymers and Ugi‐4CR in the field of multicomponent, functionalized postpolymerization modification.