Aligned hydroxyapatite nano-crystal formation on a polyamide surface. Issue 68 (5th September 2017)

• Record Type: Journal Article
• Authors: Huang, Di; Yin, Meng; Lin, Qiaoxia; Qin, Yi; Wei, Yan; Hu, Yinchun; Lian, Xiaojie; Guo, Meiqing; Du, Jingjing; Chen, Weiyi
• Is Part Of: RSC advances. Volume 7:Issue 68(2017)
• Page Start: 43040
• Page End: 43046
• Publication Date: 2017-09-05
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c7ra07182e
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : Highly aligned n-HA arrays were fabricated on polyamide matrix. The oriented nHA crystals show excellent cell response and the mechanism of how these structures form was explored. Abstract : Controlling the orientation of well-crystallized nano-hydroxyapatite (n-HA) remains a difficult task because of the complicated process of n-HA crystallization. In the present research, highly aligned n-HA arrays were fabricated on a polyamide matrix. The oriented n-HA crystals were characterized by scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), high-resolution transmission electron microscopy (HRTEM), X-ray diffraction (XRD), X-ray photoelectric spectroscopy (XPS) and Fourier-transform infrared spectroscopy (FTIR). The mechanism of how these structures form was explored. The results show that the oriented n-HA arrays are formed on a calcium treated polyamide matrix. The diameter of the n-HA columns is about 47.41 ± 3.02 nm. The n-HA crystals grow vertically with the substrate and the length of the crystals is 613.423 ± 61.57 nm. Osteoblast-like MG63 cells were cultured on the nano-crystals in order to demonstrate the biocompatibility of these oriented n-HA crystals. The MTT assay suggests that the oriented n-HA crystals could promote cell proliferation. The overall results indicate the promising potential of oriented n-HA crystals for bone regeneration.