Adherence to Guidelines for Treating Community‐Acquired Pneumonia at a New Zealand Hospital. (December 2013)

• Record Type: Journal Article
• Authors: Aikman, Kiri L; Hobbs, Mark R; Ticehurst, Robert; Karmakar, Gonesh C; Wilsher, Margaret L; Thomas, Mark G
• Is Part Of: Journal of pharmacy practice and research. Volume 43:Number 4(2013:Dec.)
• Page Start: 272
• Page End: 275
• Publication Date: 2013-12
• Subjects: Hospital pharmacies -- Australia -- Periodicals; Pharmacy -- Periodicals; Pharmacology -- Periodicals; 615.1
• DOI: 10.1002/j.2055-2335.2013.tb00273.x
• Languages: English
• ISSNs: 1445-937X

Abstract

ABSTRACT: Background: Adherence to guidelines for community‐acquired pneumonia (CAP) has been shown to improve patient outcomes and slow the emergence of antimicrobial resistance. Guidelines for treating CAP vary considerably. Aim: To determine the initial antimicrobial therapy used in hospitalised adults with CAP and to compare it with local and international CAP treatment guidelines. Method: A retrospective cohort study of adults presenting to an Auckland hospital with CAP. Initial choice of antimicrobial therapy was compared to the local hospital guidelines and the British Thoracic Society (BTS), Infectious Diseases Society of America/American Thoracic Society (IDSA/ATS) and Swedish Society of Infectious Diseases (SSID) guidelines. Results: Initial treatment in 177 patients presenting with their first episode of CAP included parenteral cephalosporin (61%), amoxycillin+clavulanate (37%), amoxycillin (2.8%) and macrolide (53%). 83/92 (90%) patients with a CURB‐65 score of 0–1 were treated with a cephalosporin or amoxycillin+clavulanate. 42/85 (49%) patients with a CURB‐65 score ≥ 2 were treated with a macrolide. Adherence with treatment guidelines was 97% (hospital), 53% (IDSA/ATS), 11% (BTS) and 10% (SSID). Conclusion: Initial treatment of adults with CAP adhered closely with local guidelines was discordant with the BTS and SSID guidelines.