A pooled analysis of combined liver and inferior vena cava resection for hepatic malignancy. Issue 9 (September 2017)

• Record Type: Journal Article
• Authors: Zhou, Yanming; Wu, Lupeng; Xu, Dong; Wan, Tao; Si, Xiaoying
• Is Part Of: HPB. Volume 19:Issue 9(2017)
• Page Start: 768
• Page End: 774
• Publication Date: 2017-09
• Subjects: Liver -- Diseases -- Periodicals; Biliary tract -- Diseases -- Periodicals; Pancreas -- Diseases -- Periodicals; 616.362005
• DOI: 10.1016/j.hpb.2017.05.008
• Languages: English
• ISSNs: 1365-182X

Abstract

Abstract: Background: Limited data are currently available to address the safety and efficacy of combined resection of the liver and inferior vena cava (IVC) for hepatic malignancies. Methods: A systematic review was performed to identify relevant studies. Pooled individual data were examined for the clinical outcome of combined resection of the liver and IVC for hepatic malignancies. Results: A total of 258 patients were described in 38 articles eligible for inclusion. Resections were performed for colorectal liver metastasis (CLM) [n = 128 (50%)], intrahepatic cholangiocarcinoma (ICC) [n = 51 (20%)], hepatocellular carcinoma (HCC) [n = 48 (19%)], and other pathologies [n = 31 (11%)]. There were 14 (5%) perioperative deaths. The median survival duration was 34 months, and the 1-, 3- and 5-year overall survival (OS) rate was 79%, 46% and 33%, respectively. The 5-year OS rate was 26% for CLM, 37% for ICC, and 30% for HCC. Conclusion: Combined resection of the liver and IVC for hepatic malignancies is safe and applicable, and offers acceptable survival outcomes.