Cationic antimicrobial copolymer poly (methylmethacrylate‐co‐PHMG) decontaminates water†. (10th March 2016)

• Record Type: Journal Article
• Authors: Aviv, Oren; Ratner, Stanislav; Amir, Nir; Laout, Natalia; Basu, Arijit; Shadmon, Hodaya; Beyth, Nurit; Domb, Abraham J.
• Other Names: Grijpma Dirk W. guestEditor.; Lendlein Andreas guestEditor.
• Is Part Of: Polymers for advanced technologies. Volume 28:Number 10(2017)
• Page Start: 1334
• Page End: 1338
• Publication Date: 2016-03-10
• Subjects: cationic polymer -- water decontamination -- poly(hexamethylene guanidine) hydrochloride -- antimicrobial; Polymers -- Periodicals; 668.9
• DOI: 10.1002/pat.3770
• Languages: English
• ISSNs: 1042-7147

Abstract

Abstract : Vinyl terminated poly hexamethylene guanidine hydrochloride (PHMG) and methyl methacrylate (MMA) were copolymerized and tested for surface antimicrobial activity. PHMG chains of molecular weight ~2000 were functionalized with vinyl end groups (PHMG–C = C) by reacting the PHMG amino end groups with 1, 2‐epoxy‐9‐decene, or glycidyl methacrylate. PHMG–C = C was copolymerized with MMA at 10% w/w ratio to form water insoluble poly(MMA‐co‐PHMG). Films of these copolymers demonstrated strong antimicrobial activity for 3 months against Escherichia coli and heterotrophic plate count bacteria. The synthesized PHMG–MMA copolymers may be used for self‐sterilizing coatings and water decontamination. Copyright © 2016 John Wiley & Sons, Ltd.