Intravascular large B‐cell lymphoma presenting as Richter's syndrome with cerebral involvement in a patient with chronic lymphocytic leukemia. Issue 9 (20th July 2017)

• Record Type: Journal Article
• Authors: Puckrin, Robert; Pop, Paula; Ghorab, Zeina; Keith, Julia; Chodirker, Lisa; Lin, Yulia; Callum, Jeannie
• Is Part Of: Clinical case reports. Volume 5:Issue 9(2017)
• Page Start: 1444
• Page End: 1449
• Publication Date: 2017-07-20
• Subjects: Chronic lymphocytic leukemia -- intravascular large B‐cell lymphoma -- meningeal lymphomatosis -- Richter's transformation; Medicine -- Periodicals; 616.09
• DOI: 10.1002/ccr3.1087
• Languages: English
• ISSNs: 2050-0904

Abstract

Key Clinical Message: Intravascular large B‐cell lymphoma (IVLBCL) is an aggressive non‐Hodgkin's lymphoma which can present with B symptoms, rash, and neurological deterioration. Up to 10% of cases of IVLBCL are associated with other hematological neoplasms, including this extremely rare presentation of IVLBCL as Richter's transformation in chronic lymphocytic leukemia. Abstract : Intravascular large B‐cell lymphoma (IVLBCL) is an aggressive non‐Hodgkin's lymphoma which can present with B symptoms, rash, and neurological deterioration. Up to 10% of cases of IVLBCL are associated with other hematological neoplasms, including this extremely rare presentation of IVLBCL as Richter's transformation in chronic lymphocytic leukemia.