Chemico-physical and antifungal properties of poly(butylene succinate)/cavoxin blend: Study of a novel bioactive polymeric based system. (September 2017)

• Record Type: Journal Article
• Authors: Santagata, Gabriella; Valerio, Francesca; Cimmino, Alessio; Dal Poggetto, Giovanni; Masi, Marco; Di Biase, Mariaelena; Malinconico, Mario; Lavermicocca, Paola; Evidente, Antonio
• Is Part Of: European polymer journal. Volume 94(2017)
• Page Start: 230
• Page End: 247
• Publication Date: 2017-09
• Subjects: Food mold -- Cavoxin -- Antifungal activity -- Poly(butylene succinate) -- Bioactive-packaging film -- Polymeric surface hydrolysis; Polymers -- Periodicals; Polymerization -- Periodicals; Polymères -- Périodiques; Polymérisation -- Périodiques; Polymerization; Polymers; Periodicals; Electronic journals; 547.705
• DOI: 10.1016/j.eurpolymj.2017.07.004
• Languages: English
• ISSNs: 0014-3057

Abstract

Graphical abstract: Highlights: Bioactive eco-friendly poly(butylenesuccinate)-cavoxin based films. Cavoxin was fungicide against Penicil roqueforti and Asperg niger, food contaminants. Spectroscopic analysis evidenced physical interaction between polymer and cavoxin. The blend was thermally stabilized and cavoxin was a nucleating agent of the polymer. Polymeric surface hydrolysis induced by cavoxin allowed its diffusion and release. Gel permeation chromatography and morphological analysis pointed out polymeric hydrolysis. Abstract: This manuscript describes antifungal, structural, thermal and morphological properties of a novel, eco-friendly bioplastic film, based on poly(butylenesuccinate) and cavoxin, a chalcone phytopathogenic metabolite, isolated from cultures by the fungus Phoma cava and included inside the biodegradable polymeric matrix. The antagonistic activity of the film explored against two fungal food contaminants Penicilliumroqueforti and Aspergillusniger, highlighted that cavoxin was fungicide at MIC concentrations. The chemico-physical analysis were performed on films before and after antifungal activity. Thermal analysis evidenced both the higher thermal stability of poly(butylenesuccinate) and cavoxin blend and the sharp nucleating action of cavoxin on the polymer. Infrared spectroscopy highlighted the presence of physical interaction between the polar groups of the blend components, whereas gel permeation chromatography highlighted that the hydrolytic effect of cavoxin on poly(butylenesuccinate) was responsible for the diffusion and releasing of the biomolecule from the matrix and UV–Vis spectroscopy provided quantitative information of release kinetics. Finally, morphological analysis confirmed both the polymeric surface hydrolysis exerted by cavoxin, and the adhesion of fungal spores on films after contact occurred during the antifungal assay.