Turn on fluorescent detection of hydrazine with a 1, 8-naphthalimde derivative. (December 2017)

• Record Type: Journal Article
• Authors: Shi, Bingjie; He, Yangyang; Zhang, Panpan; Wang, Yulong; Yu, Mingming; Zhang, Hongyan; Wei, Liuhe; Li, Zhanxian
• Is Part Of: Dyes and pigments. Volume 147(2017)
• Page Start: 152
• Page End: 159
• Publication Date: 2017-12
• Subjects: Fluorescent probe -- Off-on -- 1, 8-naphthalimde -- Hydrazine -- Fluorescence imaging; Dyes and dyeing -- Periodicals; Pigments -- Periodicals; 667.2
• DOI: 10.1016/j.dyepig.2017.08.010
• Languages: English
• ISSNs: 0143-7208

Abstract

Abstract: It is crucial to develop highly sensitive and selective probes toward hydrazine because it is a class of highly toxic and pollutant compound. Herein, using fracture of carbon carbon double bond and dissociation of amide by hydrazine, a novel off-on fluorescent probe was developed for hydrazine. The probe can quantitatively detect hydrazine in concentration range from 0 to 20 μM with the LOD of 140 nM. Further, it displayed excellent selectivity and anti-interference ability over many neutral molecules, metal ions, anions, and biological species. The ability to target lysosome and the response of hydrazine to this probe in a living cell was successfully tracked via fluorescence imaging. Graphical abstract: It is crucial to develop highly sensitive and selective probes toward hydrazine because it is a class of highly toxic and pollutant compound. Herein, using fracture of carbon carbon double bond and dissociation of amide by hydrazine, a novel off-on fluorescent probe was developed for hydrazine. The probe can quantitatively detect hydrazine in concentration range from 0 to 20 μM with the LOD of 140 nM. Further, it displayed excellent selectivity and anti-interference ability over many neutral molecules, metal ions, anions, and biological species. The response of hydrazine to this probe in a living cell was successfully tracked via fluorescence imaging. Highlights: A highly selective fluorescent probe for hydrazine shows off-on property. The probe can quantitatively detect hydrazine in the concentration range from 0 to 20 μM. The detection limit on fluorescence response of the probe can be as low as 140 nM.