Genetic polymorphisms of human platelet antigens in Euro-African and Japanese descendants from Parana, Southern Brazil. (18th August 2017)

• Record Type: Journal Article
• Authors: Silvestre, Ana Paula Avenia; Zacarias, Joana Maira Valentini; Guelsin, Gláucia Andréia Soares; Visentainer, Jeane Eliete Laguila; Sell, Ana Maria
• Is Part Of: Platelets. Volume 28:Number 6(2017)
• Page Start: 607
• Page End: 610
• Publication Date: 2017-08-18
• Subjects: Allele frequency -- genotyping -- HPA -- polymorphisms; Blood platelets -- Periodicals; Blood Platelets -- Periodicals; 615.39
• DOI: 10.1080/09537104.2016.1257785
• Languages: English
• ISSNs: 0953-7104

Abstract

Abstract: The frequency distributions of HPA-1 to HPA-6 and HPA-15 were evaluated in two Brazilian populations from Parana: a mixed population of predominantly Caucasians and a population of Japanese descendants. Genotyping was performed by PCR-SSP in 364 unrelated individuals. Differences in the distribution of HPA highlight diversity in Brazilian miscegenation and the importance of formation of the HPA panel composed of regional blood donors.