Colorimetric sensor for highly sensitive and selective detection of copper ion. Issue 35 (29th August 2017)

• Record Type: Journal Article
• Authors: Gao, Qi; Ji, Ling; Wang, Qiaoning; Yin, Kun; Li, Jinhua; Chen, Lingxin
• Is Part Of: Analytical methods. Volume 9:Issue 35(2017)
• Page Start: 5094
• Page End: 5100
• Publication Date: 2017-08-29
• Subjects: Chemistry, Analytic -- Periodicals; Analytical biochemistry -- Periodicals; Chemical laboratories -- Standards -- Periodicals; 543.1905
• DOI: 10.1039/c7ay01335c
• Languages: English
• ISSNs: 1759-9660

Abstract

Abstract : Colorimetric detection of Cu 2+ based on the inhibiting effect of Cu 2+ on the reaction ofl -cysteine with the established probe Cy-NB. Abstract : The copper ion (Cu 2+ ), as a type of essential element, plays important roles in various metabolic processes of organisms. However, an excessive intake of Cu 2+ can induce a series of diseases, such as Alzheimer's disease, Menkes disease and Wilson's disease. Therefore, it is urgently needed to develop an analytical method to achieve a simple and sensitive detection of Cu 2+ . In this study, a colorimetric sensor for the detection of Cu 2+ with a high sensitivity and selectivity has been developed. The design of the colorimetric sensor is based on the inhibiting effect of Cu 2+ on the reaction ofl -cysteine with our established probe Cy-NB. A significant color change could be directly observed by the naked eye as the concentration of Cu 2+ increases. The as-prepared colorimetric sensor has a high sensitivity with a low detection limit of 8.6 nM, and a distinguishing recognition selectivity for Cu 2+ over other possibly co-existent metal ions. Moreover, the sensor was successfully utilized for the analysis of tap water, seawater and biosamples, and high recoveries at two spiking levels of Cu 2+ ranged from 102 to 114%. The results were consistent with those obtained by ICP-MS, indicating that the developed colorimetric sensor has great application potential as a simple highly sensitive and selective detection method for Cu 2+ .