Gastrointestinal Stromal Tumors and Associated Tumors. (15th June 2017)

• Record Type: Journal Article
• Authors: Kuroiwa, Joshua; Lisanti, Christopher; Smith, Nathaniel; Schwope, Ryan; Walker, Kyle; Bui-Mansfield, Liem T.
• Is Part Of: Contemporary diagnostic radiology. Volume 40:Number 12(2017:Jun. 15)
• Publication Date: 2017-06-15
• Subjects: Gastrointestinal Stromal Tumors (GISTs) -- Associated Tumors With GISTs -- Imaging of GISTs -- GIST Syndromes -- Treatment of GISTs; Medical radiology -- Periodicals; Diagnosis, Radioscopic -- Periodicals; Diagnosis -- Periodicals; Radiology -- Periodicals; Diagnosis, Radioscopic; Medical radiology; Periodicals; 616.0757
• DOI: 10.1097/01.CDR.0000520093.21355.57
• Languages: English
• ISSNs: 0149-9009

Abstract

Abstract : Gastrointestinal stromal tumor (GIST) is the most common mesenchymal tumor in the gastrointestinal tract. GISTs are found most commonly in the stomach; followed by the small bowel, colon and rectum, esophagus, and extragastrointestinal tract. On initial staging evaluation of GISTs, the radiologist must determine the organ of origin; size; local invasion; and distant metastases, typically to the liver and peritoneum. If additional lesions are found in other locations, then syndromes related to GISTs must be considered. These include Carney triad, Carney-Stratakis syndrome, neurofibromatosis type 1 (NF1), and familial GIST syndrome. During follow-up imaging, the tasks of the radiologist are to detect residual or recurrent disease, evaluate response to therapy, and identify distant metastases while being vigilant for nonsyndromic metachronous tumors.