Reconstructing pedigrees using probabilistic analysis of ISSR amplification. (7th January 2017)

• Record Type: Journal Article
• Authors: Chaumont, Loïc; Malécot, Valéry; Pymar, Richard; Sbai, Chaker
• Is Part Of: Journal of theoretical biology. Volume 412(2017)
• Page Start: 8
• Page End: 16
• Publication Date: 2017-01-07
• Subjects: 92D25 -- 92D10 -- 60F15; Pedigree -- ISSR amplification -- Law of reproduction -- Gene frequency; Biology -- Periodicals; Biological Science Disciplines -- Periodicals; Biology -- Periodicals; Biologie -- Périodiques; Theoretische biologie; Biology; Periodicals; 571.05
• DOI: 10.1016/j.jtbi.2016.09.014
• Languages: English
• ISSNs: 0022-5193

Abstract

Abstract: Data obtained from ISSR amplification may readily be extracted but only allows us to know, for each gene, if a specific allele is present or not. From this partial information we provide a probabilistic method to reconstruct the pedigree corresponding to some families of diploid cultivars. This method consists in determining for each individual what is the most likely couple of parent pair amongst all older individuals, according to some probability measure. The construction of this measure bears on the fact that the probability to observe the specific alleles in the child, given the status of the parents does not depend on the generation and is the same for each gene. This assumption is then justified from a convergence result of gene frequencies which is proved here. Our reconstruction method is applied to a family of 85 living accessions representing the common broom Cytisus scoparius . Abstract : Highlights: Provide a probabilistic method to reconstruct the pedigree corresponding to some families of diploid cultivars. Determine for each individual what is the most likely couple of parent pair amongst all older individuals. Prove that the probability to observe the specific alleles does not depend on the generation. Application to a family of 85 living accessions representing the common broom Cytisus scoparius .