Angiographic and clinical outcomes after recanalization of coronary chronic total occlusions with the Orsiro sirolimus-eluting stent compared with the resolute zotarolimus-eluting stent. Issue 5 (August 2017)

• Record Type: Journal Article
• Authors: Markovic, Sinisa; Lützner, Michael; Dragomir, Sergiu; Rottbauer, Wolfgang; Wöhrle, Jochen
• Is Part Of: Coronary artery disease. Volume 28:Issue 5(2017:Aug.)
• Publication Date: 2017-08
• Subjects: chronic total occlusion -- drug-eluting stent -- quantitative coronary analysis; Coronary heart disease -- Periodicals; Coronary Disease -- Indexes; Coronary Disease -- Periodicals; 616.123005
• DOI: 10.1097/MCA.0000000000000470
• Languages: English
• ISSNs: 0954-6928

Abstract

Abstract : Objective: The third generation drug eluting Orsiro stent had shown already promising results in non-complex lesions. Background: We evaluated angiographic and 24 month clinical results of the sirolimus eluting Orsiro stents (O-SES) after recanalization of coronary chronic total occlusions (CTO). Results were compared with the zotarolimus eluting Resolute Integrity (R-ZES). Methods: In a prospective series 57 patients were treated with a R-ZES followed by 74 patients treated with a O-SES stent. Angiographic follow up after 9 months and clinical follow-up after 12 and 24 months was performed. Results: In-stent late lumen loss was 0.24±0.53 mm for the O-SES compared with 0.59±0.72 ( P =0.01) for R-ZES. Rates for TLR were similar (O-SES 10.0% versus R-ZES 11.1%, P =0.84). There was no definite stent thrombosis. Conclusion: The O-SES resulted in a significant lower late lumen loss but with similar clinical results up to 24 month compared to the R-ZES after treatment of CTO lesions.