18F-Sodium Fluoride PET/CT in Paget Disease. (July 2017)

• Record Type: Journal Article
• Authors: Cucchi, Francesca; Simonsen, Lene; Abild-Nielsen, Annemette Geilager; Broholm, Rikke
• Is Part Of: Clinical nuclear medicine. Volume 42:Number 7(2017)
• Publication Date: 2017-07
• Subjects: 18F-NaF PET/CT -- bone metastases -- iliac bone -- Paget disease; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000001687
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: Paget disease (PD) of bone is a benign but chronic disorder of bone metabolism. We report a case of an 85-year-old man with several fractures in the pelvis and radiograph raising suspicion of metastases. An 18 F-NaF PET/CT demonstrated high 18 F-NaF uptake in the same regions. The integrated assessment of imaging findings, supported by biochemistry, allowed diagnosing PD. The 18 F-NaF PET/CT is a supplementary diagnostic instrument in the diagnosis of PD, and use of 18 F-NaF PET/CT in this context, especially finalized to the differential diagnosis with metastatic lesions, requires the physician to be familiar with imaging patterns of this disease.