Incidental Prostate-Specific Membrane Antigen Uptake in a Peripheral Nerve Sheath Tumor. (July 2017)

• Record Type: Journal Article
• Authors: Vamadevan, Shankar; Le, Ken; Shen, Lily; Ha, Leo; Mansberg, Robert
• Is Part Of: Clinical nuclear medicine. Volume 42:Number 7(2017)
• Publication Date: 2017-07
• Subjects: 68Ga-PSMA -- nerve sheath tumor -- prostate cancer; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000001686
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: A 66-year-old man with recently diagnosed prostate cancer (Gleason score 9) was referred for 68 Ga–prostate-specific membrane antigen (PSMA) PET/CT with prostate-specific antigen level of 7.5 μg/L. PET/CT demonstrated increased PSMA uptake (SUVmax 4.7) in a soft tissue density in the left adductor compartment. MRI and cytopathology of the biopsied soft tissue density was compatible with a peripheral nerve sheath tumor. This case illustrates that PSMA uptake can occur in a peripheral nerve sheath tumor and should be taken into consideration as a benign cause of PSMA uptake.