Concomitant Lung Cancer and Gastrointestinal Stromal Tumor: First Report of Hypoxia Imaging With 18F-FAZA PET/CT. (July 2017)

• Record Type: Journal Article
• Authors: Mapelli, Paola; Incerti, Elena; Fallanca, Federico; Bettinardi, Valentino; Compierchio, Antonia; Masiello, Valeria; Doglioni, Claudio; Rossetti, Francesca; Negri, Giampiero; Gianolli, Luigi; Picchio, Maria
• Is Part Of: Clinical nuclear medicine. Volume 42:Number 7(2017)
• Publication Date: 2017-07
• Subjects: 18F-FAZA -- 18F-FDG -- GIST -- hypoxia -- lung cancer -- PET/CT; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000001704
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: A 76-year-old man underwent 18 F-FDG PET/CT to complete staging and characterize a suspicious lung mass. Images showed intense uptake in the lung lesion and faint uptake in correspondence of a gastric mass, which was subsequently biopsied revealing a gastrointestinal stromal tumor. A 18 F-FAZA PET/CT was also performed because of patient's enrollment in a prospective clinical trial (trial registration no. EudraCT 2011-002647-98), showing heterogeneous uptake of 18 F-FAZA in the pulmonary lesion and faint uptake in correspondence of the gastrointestinal stromal tumor.