A Novel Diagnostic Strategy Using 16α-[18F]-Fluoro-17-β-Estradiol (18F-FES) PET/MRI to Achieve Complete Resection of Intravenous Leiomyomatosis in Reproductive-Age Women. (July 2017)

• Record Type: Journal Article
• Authors: Chino, Yoko; Tsuyoshi, Hideaki; Tsujikawa, Tetsuya; Okazawa, Hidehiko; Yoshida, Yoshio
• Is Part Of: Clinical nuclear medicine. Volume 42:Number 7(2017)
• Publication Date: 2017-07
• Subjects: 18F-FES -- 18F-FDG -- fertility -- intravenous leiomyomatosis -- PET/MRI -- preoperative diagnosis; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000001678
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: Intravenous leiomyomatosis is a life-threatening leiomyoma that grows into the extrauterine venous system. A high recurrence rate has been reported in reproductive-age women who undergo only tumor excision to preserve fertility. Precise diagnosis of tumor extension is essential to achieve complete resection. A 24-year-old woman presented with hypermenorrhea. Contrast-enhanced MRI showed an intramural myoma with worm-like extension into the right parametrium. 18 F-FES PET/MRI accurately depicted the extension with strong FES activity into the right uterine vein, whereas 18 F-FDG PET/MRI excluded the possibility of malignancy. These modalities can be a novel strategy to manage such cases of intractable intravenous leiomyomatosis.