PVCs, PVC-Induced Cardiomyopathy, and the Role of Catheter Ablation. Issue 2 (June 2017)

• Record Type: Journal Article
• Authors: Sharma, Esseim; Arunachalam, Karuppiah; Di, Mengyang; Chu, Antony; Maan, Abhishek
• Is Part Of: Critical pathways in cardiology. Volume 16:Issue 2(2017)
• Publication Date: 2017-06
• Subjects: cardiomyopathy -- catheter ablation -- PVC; Cardiology -- Periodicals; Evidence-based medicine -- Periodicals; Medical protocols -- Periodicals; 616.12005
• DOI: 10.1097/HPC.0000000000000106
• Languages: English
• ISSNs: 1535-282X

Abstract

Abstract : Premature ventricular contractions (PVCs) are common arrhythmias noticed in the clinical setting because of premature depolarization of the ventricular myocytes. Although often thought to be reflective of underlying disease rather than intrinsically harmful, PVCs have recently been linked with worse outcomes in patients without significant cardiac disease. Long-term exposure to a high PVC burden can lead to the development of PVC-induced cardiomyopathy. The pathogenesis of this condition is poorly understood at the current time. Many studies have suggested that catheter ablation of these PVCs may result in reversal of the PVC-induced cardiomyopathy. This article will go over the natural history of PVCs and PVC-induced cardiomyopathy, as well as review the current literature on the role of catheter ablation in treating PVC-induced cardiomyopathy.