Impact of Posterior Tibial Nerve Stimulation in Treatment of Refractory Overactive Bladder Syndrome [3G]. Issue 1 (May 2017)

• Record Type: Journal Article
• Authors: Carr, Danielle; Kurdoğlu, Zehra; Kurdoğlu, Mertihan; Kilic, Gokhan
• Is Part Of: Obstetrics and gynecology. Volume 129:Issue 1(2017)
• Publication Date: 2017-05
• Subjects: Obstetrics -- Periodicals; Gynecology -- Periodicals; 618
• DOI: 10.1097/01.AOG.0000514868.14118.21
• Languages: English
• ISSNs: 0029-7844

Abstract

Abstract : INTRODUCTION: Overactive bladder (OAB) affects approximately 16% of adults in the United States. Posterior tibial nerve stimulation (PTNS) is the least invasive form of neuromodulation to treat OAB after failure of conservative therapies. In this study, we aimed to evaluate the impact of PTNS on OAB syndrome. METHODS: A retrospective study was conducted in Urogynecology Clinic between 2013 and 2016. Inclusion criteria consisted of female gender, documented clinic visit during the year before first PTNS, and completion of 12 weekly treatments. Medications used within the year before PTNS and at last follow up after PTNS were recorded. Symptom severity at first PTNS visit and after completion of PTNS was collected. Episodes of urinary frequency, leakage, and nocturia were recorded in discrete values. Urgency was reported subjectively using a scale from 1-4, with 4 being most extreme. The Wilcoxon Signed Rank Test was used for comparisons of symptom severity. RESULTS: Sixty patients in the clinic were identified with refractory OAB. Of the 46 patients receiving PTNS, 24 met inclusion criteria. Mean age was 70.25 ± 1.11 years. Mean follow up was 9.42 months. 54.17% did not require pharmacotherapy after completion of PTNS. The number of urgency episodes decreased from 3.12 to 1.79 (p=0.001), daytime frequency decreased from 7.29 to 5.58 (p=0.002), nocturia decreased from 3.33 to 2.17 (p=0.01), and leakage decreased from 2.62 to 1.33 (p=0.002). CONCLUSION: In this single center study, refractory OAB bladder responding to PTNS is slightly greater than 50% in selected patients, which agrees with the literature.