Crystal structure of dutasteride (Avodart), C27H20F6N2O2. Issue 3 (13th August 2014)
- Record Type:
- Journal Article
- Title:
- Crystal structure of dutasteride (Avodart), C27H20F6N2O2. Issue 3 (13th August 2014)
- Main Title:
- Crystal structure of dutasteride (Avodart), C27H20F6N2O2
- Authors:
- Kaduk, James A.
Crowder, Cyrus E.
Zhong, Kai
Fawcett, Timothy G.
Suchomel, Matthew R. - Abstract:
- Abstract : Commercial dutasteride crystallizes in the orthorhombic space group P 21 21 21 (#19), with a = 7.587 44(3), b = 9.960 80(5), c = 33.500 42(12) Å, V = 2531.862(17) Å 3, and Z = 4. The structure was solved and refined using synchrotron powder diffraction data, Rietveld, and density functional techniques. The most prominent feature of the structure is a zigzag chain of strong N–H···O = C hydrogen bonds along the a -axis. The powder pattern has been submitted to ICDD for inclusion in future releases of the Powder Diffraction File™.
- Is Part Of:
- Powder diffraction. Volume 29:Issue 3(2014)
- Journal:
- Powder diffraction
- Issue:
- Volume 29:Issue 3(2014)
- Issue Display:
- Volume 29, Issue 3 (2014)
- Year:
- 2014
- Volume:
- 29
- Issue:
- 3
- Issue Sort Value:
- 2014-0029-0003-0000
- Page Start:
- 274
- Page End:
- 279
- Publication Date:
- 2014-08-13
- Subjects:
- dutasteride, -- powder diffraction, -- Rietveld, -- density functional
Powder metallurgy -- Periodicals
Materials -- Analysis -- Periodicals
620.1127 - Journal URLs:
- http://journals.cambridge.org/action/displayJournal?jid=PDJ ↗
- DOI:
- 10.1017/S088571561400061X ↗
- Languages:
- English
- ISSNs:
- 0885-7156
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library STI - ELD Digital store
- Ingest File:
- 4509.xml