Contemporary diagnostics: Sarcoma pathology update. Issue 5 (17th February 2015)

• Record Type: Journal Article
• Authors: Brooks, John S.J.; Lee, Solomon
• Other Names: Kraybill William G. guestEditor.; Pollock Raphael E. guestEditor.
• Is Part Of: Journal of surgical oncology. Volume 111:Issue 5(2015:Apr. 01)
• Page Start: 513
• Page End: 519
• Publication Date: 2015-02-17
• Subjects: immunohistochemistry -- risk assessment -- new entities -- sarcoma -- new markers; Cancer -- Surgery -- Periodicals; Neoplasms -- Periodicals; 616
• DOI: 10.1002/jso.23853
• Languages: English
• ISSNs: 0022-4790

Abstract

Abstract: Sarcoma diagnosis continues to evolve as new information is discovered. Certain tumors have been downgraded (dermal leiomyosarcoma) and an atypical category designed for others. Recently entities include myxoinflammatory fibroblastic sarcoma, myoepithelioma, and pseudomyogenic hemangioendothelioma. The terms malignant fibrous histiocytoma and hemangiopericytoma are outdated. New immunostains (STAT6, SOX10, ERG) add diagnostic specificity, and new risk assessment models are described for sarcomas where grading and staging has failed to provide adequate prognosis. J. Surg. Oncol. 2015 111:513–519 . © 2015 Wiley Periodicals, Inc.