Micellar catalysis-enabled sustainable ppm Au-catalyzed reactions in water at room temperature. Issue 9 (20th July 2017)

• Record Type: Journal Article
• Authors: Klumphu, Piyatida; Desfeux, Camille; Zhang, Yitao; Handa, Sachin; Gallou, Fabrice; Lipshutz, Bruce H.
• Is Part Of: Chemical science. Volume 8:Issue 9(2017)
• Page Start: 6354
• Page End: 6358
• Publication Date: 2017-07-20
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c7sc02405c
• Languages: English
• ISSNs: 2041-6520

Abstract

Abstract : Several ppm level gold-catalyzed reactions enabled by the ligand HandaPhos can be performed at room temperature in aqueous nanoreactors composed of the surfactant Nok. Abstract : Several ppm level gold-catalyzed reactions enabled by the ligand HandaPhos can be performed at room temperature in aqueous nanoreactors composed of the surfactant Nok. Variously substituted allenes undergo cycloisomerization leading to heterocyclic products in good yields. Likewise, cyclodehydration is also illustrated under similar conditions, as is an intermolecular variant, hydration of terminal alkynes. Recycling of the catalyst and reaction medium is also illustrated. A low E factor associated with limited solvent use and therefore, waste generation, documents the greenness of this process.