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Diastereoselective synthesis of fluoroisosteric analogues of antiparasitic pyrrolobenzoxazine alkaloids from tryptophan by successive fluorination–cyclization and a Meisenheimer-type rearrangement. Issue 9 (7th June 2017)
Record Type:
Journal Article
Title:
Diastereoselective synthesis of fluoroisosteric analogues of antiparasitic pyrrolobenzoxazine alkaloids from tryptophan by successive fluorination–cyclization and a Meisenheimer-type rearrangement. Issue 9 (7th June 2017)
Main Title:
Diastereoselective synthesis of fluoroisosteric analogues of antiparasitic pyrrolobenzoxazine alkaloids from tryptophan by successive fluorination–cyclization and a Meisenheimer-type rearrangement
Abstract : Fluoroisosteric analogues of an antiparasitic pyrrolobenzoxazine alkaloid CJ-12663 were designed and diastereoselectively synthesized. Abstract : Fluoroisosteric analogues of an antiparasitic pyrrolobenzoxazine alkaloid CJ-12663 were designed and diastereoselectively synthesized by successive fluorination–cyclization and a Meisenheimer-type rearrangement from tryptophan in good yields.