Prospective study of ultrasound‐guided fine‐needle aspiration cytology and sentinel node biopsy in the staging of clinically negative T1 and T2 oral cancer. Issue 10 (21st July 2014)

• Record Type: Journal Article
• Authors: Chaturvedi, Pankaj; Datta, Sourav; Arya, Supreeta; Rangarajan, Venkatesh; Kane, Shubhada V.; Nair, Deepa; Nair, Sudhir; Chaukar, Devendra A.; Pai, Prathamesh S.; Pantvaidya, Gouri; Deshmukh, Anuja D.; Agrawal, Archi; D'Cruz, Anil K.
• Is Part Of: Head & neck. Volume 37:Issue 10(2015:Oct.)
• Page Start: 1504
• Page End: 1508
• Publication Date: 2014-07-21
• Subjects: oral cancer -- clinically negative neck -- ultrasound‐guided fine‐needle aspiration cytology -- ultrasound -- sentinel node biopsy; Head -- Diseases -- Periodicals; Neck -- Diseases -- Periodicals; Head -- Periodicals; Neck -- Periodicals; Face -- Periodicals; 617.51059
• DOI: 10.1002/hed.23787
• Languages: English
• ISSNs: 1043-3074

Abstract

ABSTRACT: Background: The purpose of this study was to compare sentinel node biopsy (SNB) and ultrasound‐guided fine‐needle aspiration cytology (FNAC) for preoperative evaluation of the N0 neck in T1 to T2 oral cavity squamous cell carcinoma (SCC). Methods: Fifty‐one consecutive patients with T1 to T2 N0 oral cavity SCC were included in this study. Preoperative ultrasound was performed in all patients. Ultrasound‐guided FNAC was performed in patients in whom the ultrasound result was reported as indeterminate or positive. SNB was done in all patients followed by elective neck dissection (END). Histopathology of END was considered as the gold standard for all statistical analysis. Results: The incidence of occult metastasis was 26.4%. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were 71.4%, 100%, 100%, and 90.2% for SNB and 14.3%, 100%, 100%, and 76.5% for ultrasound‐guided FNAC. Conclusion: Ultrasound‐guided FNAC lacked sufficient accuracy to detect occult metastases. SNB is a reliable method to detect occult metastasis that has potential to replace END. © 2014 Wiley Periodicals, Inc. Head Neck 37: 1504–1508, 2015