Cover Picture: Palladium‐Catalyzed Regioselective Allylation of Chloromethyl(hetero)arenes with Allyl Pinacolborate (Adv. Synth. Catal. 16/2017). Issue 16 (2nd August 2017) - Zhang, Sheng
Abstract : The inside cover picture, provided by Ming Bao and co‐workers, illustrates the unprecedented remote allylation of chloromethyl(hetero)arenes with allyl pinacolborate. The palladium‐catalyzed regioselective allylation reaction between chloromethyl(hetero)arenes and allyl pinacolborate proceeded smoothly via η 3 ‐benzylpalladium intermediates to provide para ‐allylated dearomatization products or para ‐allylated arenes in satisfactory to good yields; the formation of traditional Suzuki coupling products was not observed at all. This novel protocol exhibits good tolerance for various functional groups linked to (hetero)arene rings. Details of this work can be found in the communication on pages 2723–2728 (S. Zhang, A. Ullah, Y. Yamamoto, M. Bao, Adv. Synth. Catal .2017, 359, 2723–2728; DOI:10.1002/adsc.201700350 ).