A Comparative GC-MS Analysis of Bioactive Compounds in the Different Fractions of Root Extract of Oroxylum indicum (L.) Vent. Issue 3 (4th May 2017)

• Record Type: Journal Article
• Authors: Gokhale, Mamta; Gautam, Dayashankar; Khanna, Asha
• Is Part Of: Analytical chemistry letters. Volume 7:Issue 3(2017)
• Page Start: 410
• Page End: 420
• Publication Date: 2017-05-04
• Subjects: Bioactive compounds -- root extract -- isolation -- Oroxylum indicum (L.) Vent -- GC-MS; Chemistry, Analytic -- Periodicals; 543.05
• DOI: 10.1080/22297928.2017.1351889
• Languages: English
• ISSNs: 2229-7928

Abstract

Abstract: The focus of this paper is on the analytical methodologies, which include the extraction, fractionization and identification of active ingredients of root extract of medicinal tree Oroxylum indicum (L.) Vent. The genus Oroxylum indicum (L.) Vent. (Family Bignoniaceae] is a small deciduous, soft wooded tree. Every part of tree produces a broad spectrum of valuable compounds mainly flavonoids and phenolic compounds. Root of O. indicum has long been used in different ayurvedic preparations like Dashmularisht and Chyavanprash. A comparative study of compounds present in the chloroform, ethyl acetate and n-butanol fractions of root extract through gas chromatography mass spectroscopy was performed. Maximum number of compounds (50) were isolated in chloroform fraction, whereas in ethyl acetate, n-butanol and in aqueous fractions the number of compounds isolated simultaneously were 35, 24 and 22. Two compounds (9, 12-Octadecadienoic acid and baicalein) were common in all fractions. Other important compounds isolated were myristyl myristate, hydroxy methyl furfural, ascorbic acid 6 -hexadecanoate, pseudopelletierine and squalene.