Peroxidase activity of the coronene bisimide supramolecular architecture and its applications in colorimetric sensing of H2O2 and glucose. Issue 32 (15th March 2017)

• Record Type: Journal Article
• Authors: Yang, Meiding; Zhou, Huipeng; Li, Yongxin; Zhang, Qingfeng; Li, Juanmin; Zhang, Cuiyun; Zhou, Chuibei; Yu, Cong
• Is Part Of: Journal of materials chemistry. Volume 5:Issue 32(2017)
• Page Start: 6572
• Page End: 6578
• Publication Date: 2017-03-15
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Biomedical materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/c7tb00212b
• Languages: English
• ISSNs: 2050-750X

Abstract

Abstract : Distinct peroxidase-like catalytic activity of small organic probe self-assembled nanofibers is reported for the first time. Abstract : A new water soluble coronene bisimide derivative (CTDI) was designed and synthesized. CTDI self-assembled in an aqueous solution and formed supramolecular nanofibers through π–π stacking and hydrophobic interactions. The nanofibers exhibit distinct peroxidase-like catalytic activity, and can catalyze the redox reaction of 3, 3, 5, 5-tetramethylbenzidine (TMB) in the presence of hydrogen peroxide. Clear assay solution color changes were observed. The peroxidase-like catalytic property was utilized for the sensitive detection of H2 O2 and glucose. The assay shows excellent sensitivity, and 1 μM of glucose could be easily detected. Glucose detection in dilute human blood samples was also demonstrated, and the results were verified using a commercial glucose meter. Our method is simple, convenient, sensitive and selective, and could facilitate the sensing of glucose in relation to biological and biomedical research applications.