Immunoglobulin binding (B1) domain mediated antibody conjugation to quantum dots for in vitro and in vivo molecular imaging. Issue 68 (10th August 2017)

• Record Type: Journal Article
• Authors: Tsuboi, Setsuko; Sasaki, Akira; Sakata, Takao; Yasuda, Hidehiro; Jin, Takashi
• Is Part Of: Chemical communications. Volume 53:Issue 68(2017)
• Page Start: 9450
• Page End: 9453
• Publication Date: 2017-08-10
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/c7cc04966h
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : A facile method for the preparation of antibody–quantum dot conjugates using the immunoglobulin binding (B1) domain of protein G is presented. The utility of antibody–quantum dot conjugates using the B1 domain is demonstrated for fluorescence imaging of breast tumor cells in vitro and in vivo . Abstract : A facile method for the preparation of antibody–quantum dot (QD) conjugates using the immunoglobulin binding (B1) domain of protein G is presented. The utility of antibody–QD conjugates using the B1 domain is demonstrated for fluorescence imaging of breast tumor cells in vitro and in vivo .