A Scalable Biomimetic Synthesis of Resveratrol Dimers and Systematic Evaluation of their Antioxidant Activities1. (29th January 2015)
- Record Type:
- Journal Article
- Title:
- A Scalable Biomimetic Synthesis of Resveratrol Dimers and Systematic Evaluation of their Antioxidant Activities1. (29th January 2015)
- Main Title:
- A Scalable Biomimetic Synthesis of Resveratrol Dimers and Systematic Evaluation of their Antioxidant Activities1
- Authors:
- Matsuura, Bryan S.
Keylor, Mitchell H.
Li, Bo
Lin, YuXuan
Allison, Shelby
Pratt, Derek A.
Stephenson, Corey R. J. - Abstract:
- Abstract: An efficient synthetic route to the resveratrol oligomers quadrangularin A and pallidol is reported. It features a scalable biomimetic oxidative dimerization that proceeds in excellent yield and with complete regioselectivity. A systematic evaluation of the natural products and their synthetic precursors as radical‐trapping antioxidants has revealed that, contrary to popular belief, this mode of action is unlikely to account for their observed biological activity.
- Is Part Of:
- Angewandte Chemie. Volume 127:Number 12(2015)
- Journal:
- Angewandte Chemie
- Issue:
- Volume 127:Number 12(2015)
- Issue Display:
- Volume 127, Issue 12 (2015)
- Year:
- 2015
- Volume:
- 127
- Issue:
- 12
- Issue Sort Value:
- 2015-0127-0012-0000
- Page Start:
- 3825
- Page End:
- 3828
- Publication Date:
- 2015-01-29
- Subjects:
- Antioxidantien -- Biomimetische Synthese -- Chinonmethide -- Resveratrol -- Totalsynthese
Chemistry -- Periodicals
540 - Journal URLs:
- http://onlinelibrary.wiley.com/ ↗
- DOI:
- 10.1002/ange.201409773 ↗
- Languages:
- English
- ISSNs:
- 0044-8249
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 0902.000000
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 4443.xml