Blood pressure control in anticoagulated patients with hypertension and atrial fibrillation. (3rd September 2017)

• Record Type: Journal Article
• Authors: Barrios, Vivencio; Escobar, Carlos; Prieto Valiente, Luis; Lobos, Jose María; Vargas-Ortega, Diego; Polo, Jose; Marin Montañés, Nuria
• Is Part Of: Blood pressure. Volume 26:Number 5(2017)
• Page Start: 279
• Page End: 283
• Publication Date: 2017-09-03
• Subjects: Anticoagulation -- atrial fibrillation -- blood pressure control -- hypertension; Blood pressure -- Periodicals; Hypertension -- Periodicals; Hypertension -- Periodicals; Blood Pressure -- Periodicals; 612.14
• DOI: 10.1080/08037051.2017.1313094
• Languages: English
• ISSNs: 0803-7051

Abstract

Abstract: Objective: To determine the clinical profile and blood pressure (BP) control rates of anticoagulated patients with hypertension and atrial fibrillation (AF). Methods: The PAULA study was a multicenter cross-sectional/retrospective observational study conducted throughout Spain. The study included patients with nonvalvular AF who were receiving vitamin K antagonist therapy during the past year and were attended at primary care setting. Adequate BP control was defined according to 2013 ESC/ESH guidelines. Results: A total of 1, 222 hypertensive patients were included (mean age 77.9 ± 8.3 years; 51.2% women; CHADS2 2.5 ± 1.1; CHA2 DS2 -VASc 4.2 ± 1.4; HAS-BLED 1.6 ± 0.9). 33.5% of patients had diabetes, 24.9% heart failure and 14.0% prior stroke/transient ischemic attack. Mean BP was 131.4 ± 14.5/74.9 ± 9.8 mm Hg. With regard to antihypertensive treatment, most of patients were on combined therapy (67.9%). The commonest prescribed antihypertensive drugs were diuretics (64.4%), followed by angiotensin receptor blockers (30.1%), and beta blockers (29.4%). 75.2% of hypertensive patients achieved BP control targets; 86.6% of patients ≥80 years and 67.6% of diabetics. Conclusions: More than 75% of hypertensive patients with AF achieved BP goals, and this rate was higher in elderly. More than 2 thirds of patients were on combined therapy. BP control appears to be better in AF patients than in general hypertensive population.