An electrochemical biosensor for detection of the sepsis-related biomarker procalcitonin. Issue 58 (21st July 2017)

• Record Type: Journal Article
• Authors: Lim, Jong Min; Ryu, Myung Yi; Kim, Ji Hong; Cho, Chae Hwan; Park, Tae Jung; Park, Jong Pil
• Is Part Of: RSC advances. Volume 7:Issue 58(2017)
• Page Start: 36562
• Page End: 36565
• Publication Date: 2017-07-21
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1039/c7ra06553a
• Languages: English
• ISSNs: 2046-2069

Abstract

Abstract : An electrochemical peptide sensor employing a sensitive synthetic peptide was designed for the diagnosis of sepsis. Abstract : An electrochemical peptide sensor employing a sensitive synthetic peptide was designed for the diagnosis of sepsis. A series of synthetic peptides were chemically synthesized, and the binding events and performance of the sensor were monitored by CV and EIS. PCT BP3, selected as a potential high-affinity peptide, was found to have a K d value of 0.39 ± 0.11 nM for procalcitonin.