Cover Picture: Minutes Synthesis of 1, 4, 5‐Trisubstituted 5‐Dialkylamino‐1, 2, 3‐triazoles by 1‐Copper(I)‐Alkyne Controlled Tandem Process (Adv. Synth. Catal. 2‐3/2015). Issue 2 (21st January 2015)

• Record Type: Journal Article
• Authors: Wang, Bo; Liu, Nan; Chen, Wenwen; Huang, Dayun; Wang, Xinyan; Hu, Yuefei
• Is Part Of: Advanced synthesis & catalysis. Volume 357:Issue 2/3(2015)
• Page Start: 237
• Page End: 237
• Publication Date: 2015-01-21
• Subjects: click chemistry -- 1‐copper(I)‐alkynes -- cycloaddition -- tandem reactions -- 1, 4, 5‐trisubstituted 5‐dialkylamino‐1, 2, 3‐triazoles; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201500023
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract : The front cover picture, provided by Bo Wang, Xinyan Wang, and Yuefei Hu, illustrates the characteristics of 1‐copper(I)‐2‐phenylethyne in its preparation, properties and structure. By using its polymeric structure, the tandem reaction sequence of 1‐Cu(I)‐alkyne with an azide (cycloaddition) and then an electrophile E+ (electrophilic substitution) can be controlled efficiently. Thus, a general method for the synthesis of 1, 4, 5‐trisubstituted 1, 2, 3‐triazoles was developed by simply stirring the mixture of a 1‐copper(I)‐alkyne, an azide and an electroplile E+. Details can be found in the full paper on pages401–407 (B. Wang, N. Liu, W. Chen, D. Huang, X. Wang, Y. Hu, Adv. Synth. Catal. 2015, 357, 401–407; DOI: 10.1002/adsc.201400471 ).