Palladium‐Catalyzed Regioselective Allylation of Chloromethyl(hetero)arenes with Allyl Pinacolborate. Issue 16 (19th May 2017)

• Record Type: Journal Article
• Authors: Zhang, Sheng; Ullah, Aziz; Yamamoto, Yoshinori; Bao, Ming
• Is Part Of: Advanced synthesis & catalysis. Volume 359:Issue 16(2017)
• Page Start: 2723
• Page End: 2728
• Publication Date: 2017-05-19
• Subjects: allyl pinacolborate -- allylation -- catalysis -- palladium -- regioselectivity; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201700350
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: The palladium‐catalyzed regioselective allylation reaction between chloromethyl(hetero)arenes and allyl pinacolborate is reported in this work. Chloromethylarenes smoothly reacted with allyl pinacolborate, producing para ‐allylated dearomatization products or para ‐allylated arenes in satisfactory to good yields. 2‐(Chloromethyl)thiophenes and 2‐(chloromethyl)furans bearing substituents on the 5‐positions also smoothly reacted with allyl pinacolborate, producing the 5‐allylated dearomatization products in satisfactory yields. Abstract :