Catalytic carbonyl hydrosilylations via a titanocene borohydride–PMHS reagent system. Issue 16 (11th July 2017)

• Record Type: Journal Article
• Authors: Fianu, Godfred D.; Schipper, Kyle C.; Flowers II, Robert A.
• Is Part Of: Catalysis science & technology. Volume 7:Issue 16(2017)
• Page Start: 3469
• Page End: 3473
• Publication Date: 2017-07-11
• Subjects: Catalysis -- Periodicals; 541.395
• DOI: 10.1039/c7cy01088e
• Languages: English
• ISSNs: 2044-4753

Abstract

Abstract : Catalytic amounts of titanocene(iii ) borohydride, generated under mild conditions from commercially available titanocene dichloride, in concert with a stoichiometric hydride source is shown to effectively reduce aldehydes and ketones to their respective alcohols in aprotic media. Abstract : Reduction of a wide range of aldehydes and ketones with catalytic amounts of titanocene borohydride in concert with a stoichiometric poly(methylhydrosiloxane) (PMHS) reductant is reported. Preliminary mechanistic studies demonstrate that the reaction is mediated by a reactive titanocene(iii ) complex, whose oxidation state remains constant throughout the reaction.