Facile preparation of pyrimidinediones and thioacrylamides via reductive functionalization of amides. Issue 65 (2nd August 2017)
- Record Type:
- Journal Article
- Title:
- Facile preparation of pyrimidinediones and thioacrylamides via reductive functionalization of amides. Issue 65 (2nd August 2017)
- Main Title:
- Facile preparation of pyrimidinediones and thioacrylamides via reductive functionalization of amides
- Authors:
- Trillo, Paz
Slagbrand, Tove
Tinnis, Fredrik
Adolfsson, Hans - Abstract:
- Abstract : A protocol for the mild and chemoselective reductive functionalization of amides into pyrimidinediones and thioacrylamides has been developed. Abstract : The development of an efficient protocol for the reductive functionalization of amides into pyrimidinediones and amino-substituted thioacrylamides is presented. Enamines are generated in a highly chemoselective amide hydrosilylation reaction catalyzed by molybdenum hexacarbonyl in combination with 1, 1, 3, 3-tetramethyldisiloxane. The direct addition of either isocyanate or isothiocyanate generates the corresponding pyrimidinediones and 3-aminothioacrylamides in high yields.
- Is Part Of:
- Chemical communications. Volume 53:Issue 65(2017)
- Journal:
- Chemical communications
- Issue:
- Volume 53:Issue 65(2017)
- Issue Display:
- Volume 53, Issue 65 (2017)
- Year:
- 2017
- Volume:
- 53
- Issue:
- 65
- Issue Sort Value:
- 2017-0053-0065-0000
- Page Start:
- 9159
- Page End:
- 9162
- Publication Date:
- 2017-08-02
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/c7cc04170e ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 4429.xml