Oxidation-induced C–H amination leads to a new avenue to build C–N bonds. Issue 64 (26th July 2017) - Yi, Hong
Abstract : An oxidation-induced C–H functionalization leads to a new avenue to build C–N bonds, which achieves different site-selectivity compared with "classic directing-group" conditions in the reported literature. Abstract : In this work, we develop an oxidation-induced C–H functionalization strategy, which not only leads to a new avenue to build C–N bonds, but also leads to different site-selectivity compared with "classic directing-groups". The high selectivity of our new catalytic system originates from the heterogeneous electron-density distribution of the radical cation species which are induced by single electron transfer between the aromatics and oxidant-Cu(ii ) species.