Regioselective Synthesis of Heteroatom‐Functionalized Cyclobutene‐triflones and Cyclobutenones. Issue 15 (20th July 2017)

• Record Type: Journal Article
• Authors: Alcaide, Benito; Almendros, Pedro; Lázaro‐Milla, Carlos
• Is Part Of: Advanced synthesis & catalysis. Volume 359:Issue 15(2017)
• Page Start: 2630
• Page End: 2639
• Publication Date: 2017-07-20
• Subjects: alkynes -- annulation -- carbocycles -- fluorine -- synthetic methods; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201700492
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: The controlled metal‐free synthesis of a vast variety of heteroatom‐containing cyclobutene‐triflones [bis(trifluoromethylsulfonyl)cyclobutenes] and cyclobutenones has been developed starting from heteroatom‐substituted alkynes and a pyridinium salt (a latent Tf2 C=CH2 source). This powerful methodology, involving cyclization reactions, allows for the selective preparation of oxygen‐, nitrogen‐, bromine‐, chlorine‐, iodine‐, sulfur‐, selenium‐, tellurium‐, phosphorus‐, and silicon‐functionalized cyclobutene derivatives. Abstract :