High‐risk squamous cell carcinoma of the ear — A potential role for sentinel node biopsy. Issue 9 (22nd June 2017)

• Record Type: Journal Article
• Authors: Beecher, Suzanne; Wrafter, Paula F.; Joyce, Cormac W.; Regan, Padraic J.; Kelly, Jack L.
• Is Part Of: Head & neck. Volume 39:Issue 9(2017)
• Page Start: 1840
• Page End: 1844
• Publication Date: 2017-06-22
• Subjects: ear -- auricular -- sentinel lymph node biopsy -- squamous cell carcinoma (SCC); Head -- Diseases -- Periodicals; Neck -- Diseases -- Periodicals; Head -- Periodicals; Neck -- Periodicals; Face -- Periodicals; 617.51059
• DOI: 10.1002/hed.24843
• Languages: English
• ISSNs: 1043-3074

Abstract

Abstract: Background: Squamous cell carcinomas (SCCs) of the external ear have a significant rate of metastasis. The purpose of this study was to present analyzed factors associated with auricular SCC metastasis in order to identify a group that may benefit from sentinel lymph node biopsy (SLNB). Methods: We performed a retrospective review of all operable SCCs between 2009 and 2014. The association between high‐risk features and metastasis were analyzed. Results: One hundred eighty‐nine auricular SCCs were excised. Local recurrence was noted in 11% and 9.5% developed metastases. Cartilage, perineural, and lymphovascular invasion were significantly associated with metastasis, as were increased tumor depth and diameter ( P < .001). All patients with metastasis developed nodal disease. Conclusion: Factors, including poor differentiation, perineural, cartilage, and lymphovascular invasion, are associated with auricular SCC metastasis. Patients with 2 or more high‐risk features may benefit from SLNB in order to identify and treat early nodal disease and possibly reduce the risk of further spread.