Frontispiece: Gold(I)‐Catalysed Asymmetric Hydroamination of Alkenes: A Silver‐ and Solvent‐Dependent Enantiodivergent Reaction. Issue 45 (10th August 2017)

• Record Type: Journal Article
• Authors: Abadie, Marc‐Antoine; Trivelli, Xavier; Medina, Florian; Duhal, Nathalie; Kouach, Mostafa; Linden, Bernhard; Génin, Eric; Vandewalle, Maxence; Capet, Frédéric; Roussel, Pascal; Del Rosal, Iker; Maron, Laurent; Agbossou‐Niedercorn, Francine; Michon, Christophe
• Is Part Of: Chemistry. Volume 23:Issue 45(2017)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2017-08-10
• Subjects: alkenes -- enantiodivergent catalysis -- gold -- hydroamination -- silver; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201784564
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract : In the background is featured Ginkakuji (Silver Pavilion), a Zen temple along Kyoto′s eastern mountains (Higashiyama) in Japan. In the foreground is featured a chemistry sketch based on the Yin and Yang symbol. As many possible dualities (such as light and dark, fire and water…) are thought of as physical manifestations of the duality symbolised by Yin and Yang, parallels can be drawn with organic chemistry and the gold(I)‐catalysed asymmetric hydroamination of alkenes. An enantiodivergent reaction is possible depending on the presence of silver. Whereas a gold‐catalysed hydroamination reaction afforded ( S )‐product in toluene, the use of methanol led to an enantioinversion and the generation of ( R )‐product through solvation of silver and bimetallic activation of the amino‐alkene reagent. For more information see the Full Paper by F. Agbossou‐Niedercorn, C. Michon and co‐workers onpage 10777 ff.