Phase formation, microstructure and setting time of MCM-48 mesoporous silica nanocomposites with hydroxyapatite for dental applications: Effect of the Ca/P ratio. Issue 15 (15th October 2017)

• Record Type: Journal Article
• Authors: Lenji, Razieh Karimi; Nourbakhsh, Amir Abbas; Nourbakhsh, Nosrat; Nourbakhsh, Mahtab; Mackenzie, Kenneth J.D.
• Is Part Of: Ceramics international. Volume 43:Issue 15(2017)
• Page Start: 12857
• Page End: 12862
• Publication Date: 2017-10-15
• Subjects: MCM-48 -- Hydroxyapatite -- Setting time -- Nanocomposite; Ceramics -- Periodicals; Céramique industrielle -- Périodiques; Ceramics; Periodicals; Electronic journals; 666
• DOI: 10.1016/j.ceramint.2017.06.177
• Languages: English
• ISSNs: 0272-8842

Abstract

Abstract: Nanocomposites of MCM-48 mesoporous silica and hydroxyapatite (HA) are investigated as possible alternatives for the commonly used Mineral Trioxide Aggregate (MTA) dental cement, and the effect of their Ca/P ratio on their structure, properties and setting times is reported. XRD, FTIR and EDS/SEM analysis of the nanocomposites indicate that crystalline HA is formed within the mesoporous silica structure. High Ca/P ratios lead to the formation of free CaO within the nanocomposite, decreasing its setting time; the shortest setting time (~ 40 min), which occurs in the MCM-48/HA nanocomposite with a Ca/P ratio of 5, in physiological saline solution, is considerably shorter than the setting time of MTA (~ 140 min under identical conditions). Thus, the shorter setting time of the MCM-48/HA nanocomposites, coupled with their lack of toxicity, high degree of bioactivity and their stability in tissue fluids, suggest that they could serve as a useful replacement for MTA.