Chaperoning the DNA damage response. (August 2017)
- Record Type:
- Journal Article
- Title:
- Chaperoning the DNA damage response. (August 2017)
- Main Title:
- Chaperoning the DNA damage response
- Authors:
- Stracker, Travis H.
- Abstract:
- Abstract : The NBN component of the MRE11‐RAD50‐NBN (MRN) complex and the ATM kinase have been identified as clients of the HSP90α chaperone. Inhibition of HSP90 leads to reduced stability of NBN and ATM and an impaired DNA damage response. These results identify new regulatory details of the DNA damage response and further explain the chemosensitizing effects of HSP90 inhibitors.
- Is Part Of:
- FEBS journal. Volume 284:Number 15(2017)
- Journal:
- FEBS journal
- Issue:
- Volume 284:Number 15(2017)
- Issue Display:
- Volume 284, Issue 15 (2017)
- Year:
- 2017
- Volume:
- 284
- Issue:
- 15
- Issue Sort Value:
- 2017-0284-0015-0000
- Page Start:
- 2375
- Page End:
- 2377
- Publication Date:
- 2017-08
- Subjects:
- Biochemistry -- Periodicals
Molecular biology -- Periodicals
Pathology, Molecular -- Periodicals
572 - Journal URLs:
- http://firstsearch.oclc.org ↗
http://gateway.ovid.com/ovidweb.cgi?T=JS&MODE=ovid&NEWS=n&PAGE=toc&D=ovft&AN=01038983-000000000-00000 ↗
http://www.blackwell-synergy.com/servlet/useragent?func=showIssues&code=ejb ↗
http://onlinelibrary.wiley.com/ ↗
http://www.blackwell-synergy.com/servlet/useragent?func=showIssues&code=ejb ↗ - DOI:
- 10.1111/febs.14156 ↗
- Languages:
- English
- ISSNs:
- 1742-464X
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3901.578500
British Library DSC - BLDSS-3PM
British Library HMNTS - ELD Digital store - Ingest File:
- 4402.xml