Fluorescent Markers for Amyloid‐β Detection: Computational Insights. Issue 7 (1st December 2016)
- Record Type:
- Journal Article
- Title:
- Fluorescent Markers for Amyloid‐β Detection: Computational Insights. Issue 7 (1st December 2016)
- Main Title:
- Fluorescent Markers for Amyloid‐β Detection: Computational Insights
- Authors:
- Peccati, Francesca
Pantaleone, Stefano
Solans‐Monfort, Xavier
Sodupe, Mariona - Abstract:
- Abstract: In vivo detection of cerebral amyloid‐β plaques is essential for an early diagnosis of Alzheimer′s disease. Optical imaging, which employs fluorescent markers emitting in the near‐infrared range, is a growing alternative to nuclear techniques, with indisputable advantages. The rational design of amyloid markers requires optimization of both the optical and binding properties, and of their mutual interaction. In this work, the structural aspects that determine the performance of selected amyloid markers have been analyzed, focusing on the contributions offered by computational techniques. Abstract :
- Is Part Of:
- Israel journal of chemistry. Volume 57:Issue 7/8(2017)
- Journal:
- Israel journal of chemistry
- Issue:
- Volume 57:Issue 7/8(2017)
- Issue Display:
- Volume 57, Issue 7/8 (2017)
- Year:
- 2017
- Volume:
- 57
- Issue:
- 7/8
- Issue Sort Value:
- 2017-0057-NaN-0000
- Page Start:
- 686
- Page End:
- 698
- Publication Date:
- 2016-12-01
- Subjects:
- Alzheimer′s disease -- amyloid-beta peptides -- density functional calculations -- fit-induced docking -- fluorescence imaging
Chemistry -- Periodicals
540.5 - Journal URLs:
- http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1869-5868/issues ↗
http://www.sciencefromisrael.com/link.asp?id=300168 ↗
http://onlinelibrary.wiley.com/ ↗ - DOI:
- 10.1002/ijch.201600114 ↗
- Languages:
- English
- ISSNs:
- 0021-2148
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 4583.802000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 4397.xml