Formation of Phenyliodonio‐Substituted Spirofurooxindole Trifluoroacetates from N‐Substituted 3‐Oxopentanediamides via Phenyliodine Bis(trifluoroacetate)‐Mediated Oxidative Cascade Reactions. Issue 15 (28th April 2017)

• Record Type: Journal Article
• Authors: Hu, Bei; Cao, Yang; Zhang, Bobo; Zhang‐Negrerie, Daisy; Du, Yunfei
• Is Part Of: Advanced synthesis & catalysis. Volume 359:Issue 15(2017)
• Page Start: 2542
• Page End: 2548
• Publication Date: 2017-04-28
• Subjects: cascade reactions -- C(sp3)–C(sp2) bond formation -- C(sp2)–O bond formation -- hypervalent iodine(iii) reagents -- iodonio-substituted spirofurooxindole derivatives; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201700075
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: The reaction of N ‐substituted 3‐oxopentanediamides with phenyliodine bis(trifluoroacetate) (PIFA) was found to give a novel class of phenyliodonio‐substituted spirofurooxindole trifluoroacetates under metal‐free conditions. The reaction is postulated to proceed via a cascade process involving an oxidative C—O bond formation, an oxidative C—C bond formation and a final iodination step. Abstract :