A direct crossed polymerization of triphenylamines and cyclohexanones via CC bond formation: the method and its bioimaging application. (10th July 2017)

• Record Type: Journal Article
• Authors: Ma, Hengchang; Cao, Haiying; Lei, Lei; Yang, Zengming; Yang, Manyi; Qin, Yanfang; Ma, Yucheng; Guan, Xiaolin; Lu, Dedai; Lei, Ziqiang
• Is Part Of: New journal of chemistry. Volume 41:Number 16(2017)
• Page Start: 7908
• Page End: 7914
• Publication Date: 2017-07-10
• Subjects: Chemistry -- Periodicals; Chimie -- Périodiques; 540
• DOI: 10.1039/c7nj01407d
• Languages: English
• ISSNs: 1144-0546

Abstract

Abstract : Fluorescent polymers synthesized by ACC reactions with interesting optical performances and the potential cell imaging applications. Abstract : The effective polymerization process is very desirable in the field of macromolecule science. In this study, we present a facile synthetic method via aldol addition and condensation (AAC) that leads to the formation of fluorescent linear and branched polymers by cross coupling triphenylamines (TPA) and cyclohexanones (CYC) via CC bond formation. The methodology has the advantage of easy operations, mild reaction conditions, and high yield. Via the analysis of NMR, FT-IR, GPC, PL, UV, SEM, and theoretical calculation, the structure, physical properties, and optical behaviors of both polymers were well-characterized. The understanding of cell transplantation, migration, division, fusion, and lysis is a very challenging task. In this study, the linear polymer (LP) exhibits excellent biocompatibility and low cytotoxicity, which can be readily internalized by living cells in a noninvasive manner. The images of MPC5 cells indicate that LP can be a promising emissive fluorescence probe for bioimaging application.