The role of race/ethnicity in cerclage efficacy. (2nd October 2017)

• Record Type: Journal Article
• Authors: Fryer, Kimberly; Keiser, Sharon; Trofatter, Kenneth; Eichelberger, Kacey Y.; Heberlein, Emily
• Is Part Of: Journal of maternal-fetal & neonatal medicine. Volume 30:Number 19(2017)
• Page Start: 2382
• Page End: 2385
• Publication Date: 2017-10-02
• Subjects: Preterm birth -- disparities -- race/ethnicity -- cerclage; Obstetrics -- Periodicals; Perinatology -- Periodicals; Infants (Newborn) -- Diseases -- Periodicals; Neonatology -- Periodicals; 618.2
• DOI: 10.1080/14767058.2016.1249843
• Languages: English
• ISSNs: 1476-7058

Abstract

Abstract: Objective : To measure the impact of race/ethnicity on cerclage efficacy, as measured by the prevalence of spontaneous preterm birth (PTB), in a cohort of patients with history-indicated, ultrasound-indicated and physical-exam indicated cerclages. Methods : We conducted a retrospective cohort study of patients undergoing history-indicated, ultrasound-indicated and physical-exam indicated cerclage placement from January 2003 to July 2013 at a tertiary care hospital. Patients' race/ethnicity was self-declared. Our primary outcome was spontaneous preterm birth (SPTB) < 37 weeks. Subgroup analyses were performed for each of the three indications for cerclage. Results : One hundred and eighty-one subjects met inclusion criteria. Forty-seven percent self-identified as non-Hispanic black (NHB), 12% as Hispanic and 41% as non-Hispanic white (NHW). There was no significant difference in the prevalence of SPTB < 37 weeks between the three race/ethnicity groups (33% versus 19% versus 40%, respectively, p = 0.22), nor for SPTB less than 34 or 28 weeks. Finally, there was no difference in SPTB prevalence by race after controlling for smoking, history of CKC/LEEP, and 17-OHPC with logistic regression. Conclusion : Race/ethnicity does not appear to be associated with cerclage efficacy, as measured by the risk of SPTB, in a cohort of patients with history-indicated, ultrasound-indicated and physical-exam indicated cerclages.